PROJECT IDEATION, VALIDATION, AND EXECUTION
Curious to see what we’re up to?
New Frontiers For The Common Bean
Don’t let your hard work go unpublished.
70% of Americans can be classified as having either overweight or obesity. Calorie restriction is an effective short-term weight loss tool, though long-term adherence is rare, and weight re-gain is more often than not. Modification of macronutrient intake alongside calorie restriction may be an effective way to increase feelings of satiation and maintain weight loss.
Our client conducted a large-scale human trial testing their high-protein, high-fiber nutrition shake on health outcomes, but sought additional assistance with the statistical analysis and manuscript generation. We jumped at the chance to work with their team to understand their statistical analysis plan and additional analysis needs, compare intention-to-treat and per protocol analyses, and provide a submission ready manuscript at project completion.
Leveraging Science with Intellectual Property
Intellectual property is not just for lawyers. Here it played a major role in the decision to innovate new ingredients.
In their mission towards sustainability, CP Kelco wanted to combine two waste streams and upcycle them into a new product, eliminating waste and increasing their product portfolio at the same time.
We performed a two-step analysis, starting with an in-depth review of the scientific literature supporting this novel product as a prebiotic.
In parallel, we conducted a freedom-to-operate analysis to identify the existing intellectual property related to the manufacture, composition, and use of the proposed product, outlining challenges and opportunities to the production and sale of their new product.
Safety of Ingredients in Infant Formula
Pectin may be one of the world’s oldest thickeners, perhaps most known for its uses in jams and jellies. It is a fermentable and soluble fiber that can be used to thicken beverages and infant formula. As part of a call by the European Food and Safety Administration for an assessment of the safety of pectin for infants below 16 weeks of age we assisted with the publication of research on pectin’s effect on growth and nutrient digestibility in formula.
As technical writers, we relish opportunities to make stories out of data. We first began by conducting a quick literature review to identify other work in the field, compiled regulatory guidelines for use of this ingredient in pediatric products, and combed through clinical research investigating its safety.
We reviewed the data from our client, worked internally to generate a manuscript explaining the results and their biological significance, and after a 3-round review process submitted the work for publication.
Check it out here!
Nutrition and Enterotoxigenic E. Coli in Pork Production
Enterotoxigenic Escherichia coli can ravage weanling pigs, causing morbidity, mortality, and slowed growth. Producers want to protect the health of their herds, and as consumers, we want our pork to come from healthy pigs. As producers transition away from using antibiotics, the role of nutrition becomes increasingly important.
We were approached by a client to assist with the scoping, budgeting, planning, and coordination of a feed trial in weanling pigs. Leaning on our experience in animal science we scoped the budget, vetted vendors, and generated standard operating procedures and data acquisition forms. With protocols in hand, our client executed the study with their partners and provided us the data in return. After statistical analysis and review of the outcomes, we were able to provide our insight on the efficacy of their products.
The Pig as Biomedical Model
Like humans and primates, the pig brain is gyrencephalic, and growth of the pig brain follows a similar trajectory as the human. The precocial nature of the pig allows behavioral assessment during early development.
The size of the pig allows the use of the same equipment as that used in human clinical trials, whether that equipment is related to magnetic resonance imaging or medical devices. Thus, backwards validation and forward-looking innovation can be achieved in the same model.
Similar anatomy and physiology have led to the pig becoming a gold standard in nutrition science, among many other fields.
AI For Monitoring Animal Behavior
We’re partnering with Loopbio to bring video analysis of pig behavior to biomedical and agricultural research.
The ability to passively track multiple animal’s positions, postures, and behaviors will open the door to high-throughput behavior analysis and animal welfare tracking.